The 9 th International Conference for Basic Sciences
27 – 29 March, 2017, Cairo, Egypt.
The Conference will be held in Al-Azhar Conference Center (aacc), Tayaran st., Nasr City, Cairo
Energy, Environment and Sustainable Development
Basic Sciences pillar for the transition to the era of knowledge
العلوم الأساسية ركيزة ضرورية للتحول إلى عصر المعرفة

The 9 th International Conference for Basic Sciences,
   
Energy, Environment and Sustainable Delvelopment, 27 – 29 March 2017, Cairo, Egypt.

Plenary (POL) Speaker

Prof. Dr. Mahmoud Hashem Abdel- Kader
President of German University in Cairo, EG
Professor of Photochemistry
Email: mahmoud.abdelkader@guc.edu.eg
 

Abstract

Photodynamic Therapy(PDT) for Cancer Diagnosis and Treatment

 

Mahmoud H.Abdel- Kader
Professor of Photochemistry, NILES,  Cairo University
President of the German University in Cairo, New Cairo

 

Photodynamic therapy (PDT) is a promising new modality for cancer treatment, which involves the combination of light of an appropriate wavelength and a photosensitizing agent, which is selectively taken up and retained by tumor cells. Separately, each of these factors is harmless; however when they are combined in the presence of oxygen, cytotoxic reactive oxygen species are produced, which leads to irreversible cellular damage and causes cell death and tumor destruction.

PDT has been used for many years, but only now is becoming widely accepted and utilized, even though it has many advantages over other types of treatments. First, PDT avoids systemic treatment since treatment occurs only where light is delivered. Therefore it is not necessary for the patient to undergo systemic treatment when treating localized disease, therefore, side-effects are also avoided. Another advantage is that PDT is selective. The photosensitizing agent will selectively accumulate in cancer cells and the surrounding normal tissues are spared. PDT can also be used when surgery is not possible. If a patient has cancer in an organ or part of an organ that cannot be removed surgically (eg. the upper bronchi of the lung), PDT can still treat the site. Moreover, it is a  low cost procedure. Finally, PDT is a repeatable therapy. Unlike radiation therapy, PDT can be used again and again. Hence, it offers a means of long-term management of cancer even if complete cure is not possible.

In this presentation, the basic principles of PDT, as well as the fundamentals of the theory, methods, and instrumentation of clinical diagnosis and treatment of cancer will be introduced. It will also discuss non-oncological applications such as functional targeting of bacteria, and vector control of Malaria and treatment of Microbial Infections.

 

Biographical Sketch

 

Prof. Mahmoud H. Abdel-Kader
Professor of Photochemistry, Cairo University  President of the German University in Cairo
Email: Mahmoud.abdelkader@guc.edu.eg

Prof. Abdel-Kader is a Professor of Photochemistry and currently, the President of the German University in Cairo, since 2002. Prof. Abdel-Kader received his Ph.D. (Dr. rer. nat.) in Spectroscopy and Photochemistry at Stuttgart University, Germany in 1979. He got a post doctoral position at University of Karlsruhe, from 1982 to 1983. From 1983 to 1984, he was a Senior Researcher at the Federal Institute of Technology, EPFL, Lausanne, Switzerland. He was a Visiting Professor at both Georgia Institute of Technology, Atlanta, USA and the Institute for Laser Technology in Medicine and Metrology, Ulm University. He then served the position of Vice Dean of the National Institute of Laser-Enhanced Sciences (NILES), in Cairo University.

Prof. Abdel-Kader has supervised 82 master’s theses and doctoral dissertations. He has published over 100 publications in peer reviewed journals and in conference proceedings. Also, he is an inventor of 9 patents. He has given more than 80 invited talks and plenary lectures at both national and international meetings. Prof. Abdel-Kader’s research interests include: Utilization of Solar Energy in Photochemical Conversions for Malaria, Filaria and Dengue Fever Vector control, Parasites such as Schistosomiasis and Agricultural pests using environmentally friendly (natural extract) Photosensitizers and Application of Nanoparticles in Photodynamic Diagnosis and Therapy of Cancer. Prof. Abdel-Kader was elected as Officer, then Chair of the Committee of the European Society for Photobiology (ESP) activities outside Europe (1997–2001). He was awarded the distinguished State Prize in Chemistry, in Egypt, 1996 as well as the State Medal in Chemistry, 1998. Prof. Abdel-Kader was awarded the 2012 Excellence Award of Science from Cairo University. He was awarded the State Award Discretion in Advanced Technological Sciences, 2014. Recently, he was elected as a permanent member of the Scientific Institute of Egypt, 2015 (which is the most prestigious Scientific Institute in the region established in 1798).

 


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